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immunocap isac  (Thermo Fisher)


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    Structured Review

    Thermo Fisher immunocap isac
    Immunocap Isac, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/immunocap+isac+system/immunocap+system/pm40602688-83-18-20
    Average 90 stars, based on 1 article reviews
    immunocap isac - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Peptide Microarray:

    Article Title: The lung microbiota in early rheumatoid arthritis and autoimmunity
    Article Snippet: Anti-CCP2 antibodies in the serum and BAL were detected using the enzyme-linked immunosorbent assay (ELISA) (Euro-Diagnostica AB, Sweden) according to manufacturer’s instructions. .. Serum samples were analyzed for specific ACPA IgGs using a custom-made peptide microarray based on the ImmunoCAP ISAC system (PhaDia) described in detail earlier [ ]. ..

    Article Title: Association between number and type of different ACPA fine specificities with lung abnormalities in early, untreated rheumatoid arthritis
    Article Snippet: .. We further assessed ACPA fine specificity against 10 different citrullinated antigens using a custom-made peptide microarray based on the ImmunoCAP ISAC system (Phadia) described previously in detail. ..

    Microarray:

    Article Title: Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides
    Article Snippet: .. The microarray is based on Phadia's ImmunoCAP ISAC system, with which reactivity to more than 100 antigens can be analyzed simultaneously, by using minute serum volumes (< 10 μl). ..

    Article Title: Number of individual ACPA reactivities in synovial fluid immune complexes, but not serum anti-CCP2 levels, associate with inflammation and joint destruction in rheumatoid arthritis
    Article Snippet: .. ACPA in serum and SF and in solubilised IC from serum and SF were investigated on a custom-made microarray based on the ImmunoCAP ISAC system (Phadia AB, Uppsala, Sweden). ..

    Article Title: Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis
    Article Snippet: All patients fulfilled the 1987 ACR RA classification criteria ( ) and were subgrouped as ACPA seropositive (193 subjects) or seronegative (50 subjects) using the anti-CCP2 assay (CCPlus, Euro Diagnostica). .. Patient samples have previously been screened for anti-citrullinated peptide fine-specificities with an antigen microarray multiplex assay, based on Phadia's ImmunoCAP ISAC system, as previously described ( ). ..

    Article Title: Anticitrullinated protein/peptide antibody multiplexing defines an extended group of ACPA-positive rheumatoid arthritis patients with distinct genetic and environmental determinants.
    Article Snippet: Introduction the second generation anticycliccitrullinated peptide (anti-CCp2) assay detects the majority but not all anticitrullinated protein/peptide antibodies (ACpA).. Anti-CCp2-positive rheumatoid arthritis (rA) is associated with HLA-drB1* shared epitope (SE) alleles and smoking.. Using a multiplex assay to detect multiple specific ACpA, we have investigated the fine specificity of individual ACpA responses and the biological impact of additional ACpA reactivity among anti-CCp2-negative patients.

    Multiplex Assay:

    Article Title: Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis
    Article Snippet: All patients fulfilled the 1987 ACR RA classification criteria ( ) and were subgrouped as ACPA seropositive (193 subjects) or seronegative (50 subjects) using the anti-CCP2 assay (CCPlus, Euro Diagnostica). .. Patient samples have previously been screened for anti-citrullinated peptide fine-specificities with an antigen microarray multiplex assay, based on Phadia's ImmunoCAP ISAC system, as previously described ( ). ..

    Article Title: The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy
    Article Snippet: .. Analysis of 16 ACPA reactivities and the corresponding native arginine-containing control peptides targeting citrullinated peptides from fibrinogen (Fib), alpha-1 enolase (citrullinated enolase peptide 1 (CEP-1)), vimentin (Vim), filaggrin (Fil) and histone (H) was performed using a multiplex chip-based assay based on the ImmunoCAP ISAC system (Phadia AB, Uppsala, Sweden) [ , ]. ..

    Control:

    Article Title: The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy
    Article Snippet: .. Analysis of 16 ACPA reactivities and the corresponding native arginine-containing control peptides targeting citrullinated peptides from fibrinogen (Fib), alpha-1 enolase (citrullinated enolase peptide 1 (CEP-1)), vimentin (Vim), filaggrin (Fil) and histone (H) was performed using a multiplex chip-based assay based on the ImmunoCAP ISAC system (Phadia AB, Uppsala, Sweden) [ , ]. ..

    Construct:

    Article Title: Anticitrullinated protein/peptide antibody multiplexing defines an extended group of ACPA-positive rheumatoid arthritis patients with distinct genetic and environmental determinants.
    Article Snippet: Introduction the second generation anticycliccitrullinated peptide (anti-CCp2) assay detects the majority but not all anticitrullinated protein/peptide antibodies (ACpA).. Anti-CCp2-positive rheumatoid arthritis (rA) is associated with HLA-drB1* shared epitope (SE) alleles and smoking.. Using a multiplex assay to detect multiple specific ACpA, we have investigated the fine specificity of individual ACpA responses and the biological impact of additional ACpA reactivity among anti-CCp2-negative patients.



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